Presentation of the Centre
Biomedical Research Center of the Slovak Academy of Sciences (BMC SAS) is a multidisciplinary institute devoted to basic, translational and clinical research. The Centre was established through merge of five previously independent SAS institutes including Cancer Research Institute (CRI).
Main Research Activities
BMC SAS research activities focus on understanding mechanisms of human diseases and comorbidities that represent major healthcare and socio-economic burden, including cancer. Major research topics of the CRI BMC SAS involve molecular mechanisms and phenotype of cancer, cancer genetics and epigenetics, DNA damage and repair, mesenchymal stem cells, tumour microenvironment and heterogeneity, mechanisms of chemoresistance, mutagenic and carcinogenic activities of various chemicals, newly developed chemotherapeutics, the effects of phytochemicals on cancer cells, nanomaterials useful in clinical oncology, biomarkers for cancer diagnostics, prediction of therapy outcome and stratification of patients, bench-to-bedside translation and prevention strategies.
Core Facilities
Major infrastructures are encompassed in the Laboratory for Cytoanalytics (Altra, BD Canto II, FACS Aria II cytometer & sorter, ImageStream cytometer, IncuCyte ZOOM, Helios and Hyperion CyTOF), Bioimaging Laboratory (IVIS Spectrum CT, Zeiss LSM 510 Meta confocal microscope), Animal Facility for Immunodefficient Mice, Outpatient Research Clinic and Centre of Physical Activity.
Education
BMC SAS is approved to provide PhD education in 11 programs including oncology. Additional education activities comprise lecturing at major Slovak universities and supervision of diploma theses